Welcome to dash-and-sign blogspot!
We are the dash- Cecilia and the sign- Keionn :DThis blog will be featuring our project main topic: pyruvate dehydrogenase complex deficiency.
A little trivia on us: we are students who like science~ :D
Hope that you will find this blog informative and interesting. Please follow us with interest!
That's all folks~
With love,
dash-and-sign bloggers
HELLO KEIONN AND CECILIA!
ReplyDeleteWhat i like about you blog!: I think that your blog is very well done and is very detailed which i think will help us even understand the lectures even better. I think this is relatable as we learn about pyruvate and the kreb cycle during our lecture.
What i learnt from your blog: I learnt that this deficieny is a X-linked disease which we got from the sex chromosome and also that pyruvate dehydrogenase complex deficiency is usually caused by a deficiency of one or more enzymes or cofactors that are needed for chemical reaction in the cells of the body.
I also learnt the signs and symptoms of it which we can take note next time if we need to!
What can be improved on:
I think that your blog is a bit too complex and relatively more difficult to understand if i was not a science students. So maybe some of the words you could use more laymen terms and words so even non-science students can understand! :D
Also, you can put more cute relevant pictures to make the blog even more lively and cheerful so it will not be so serious and wordy!
OVERALL I THINK BOTH OF YOU REALLY DID AN AWESOME JOB! *pats both of your back*
Hello :)))))
ReplyDeleteWhat I've learned about your blog:
I have learnt that people who have pyruvate dehydrogenase complex deficiency are unable to convert pyruvate to acetyl-CoA. This means that the body cells are not able to undergo Kreb's cycle which is a huge problem!
After reading your blog, I have learnt that patients with this deficiency develops neurological and metabolic disabilities.
After reading the treatments section, I realised that the diet recommended for the patients would be a high protein, fat and a low carbohydrate diet. Out of interest, I would like to ask if the patients undergoing this diet will grow fat and will this lead to further health problems? (since it is a high fat/protein diet) :P
Anyway, good job on completing the blog! :) I enjoyed reading it!
I already find it very hard to live a life with little energy. It must be really hard for these people whose body can't go through the Krebs cycle because their body can't convert pyruvate. Much more energy can't be produced as there would be no NADH and FADH2 produced from the Krebs cycle to undergo the electron transport chain. I hope such there can will be a cure for these diseases, instead of having the patients having to constantly having a supplemented diet
ReplyDelete